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Temporal Analysis of Meiotic DNA Double-Strand Break Formation and Repair in Drosophila Females

Figure 4

Frequency of γ-His2Av Foci Induced with 10 Gy of X-Rays as a Function of Meiotic Stage and Time since Exposure

Average number of γ-His2Av foci observed in mei-W68⁴⁵⁷² (blue), mei-P22¹⁰³ (orange), okr^WS mei-W68⁴⁵⁷² (green), and mei-P22¹⁰³ spn-B^BU (purple) at 1 h (A), 5 h (B), and 24 h (C) after irradiation. In region 2a pro-oocytes 5 h after irradiation, okr^WS mei-W68⁴⁵⁷² pro-oocytes had 24.8% of the γ-His2Av foci found in mei-W68⁴⁵⁷², and mei-P22¹⁰³ spn-B^BU had 33.6% of the foci found in mei-P22¹⁰³. Data for the 24-h timepoint in mei-P22¹⁰³ spn-B^BU was not collected.

doi: https://doi.org/10.1371/journal.pgen.0020200.g004