In this issue: Inbreeding and wild tigers at risk of extinction, temperature and aging in frogs and toads, and ancient diets in the Andes. http://ow.ly/23pR50H5wrv
A reduction in male canine tooth size and, possibly, aggression occurred at least 4.5 million years ago, suggesting that weak canine tooth sexual dimorphism characterized members of the human clade early on. http://ow.ly/hPFK50H5v5M
A click chemistry-enabled CRISPR screening platform illustrates how emergent chemical biology approaches can expand the power of genome-wide CRISPR screening to elucidate mechanisms regulating specific enzyme-driven signaling pathways. In PNAS: http://ow.ly/FfFL50H5v0M
Multiscale phase-contrast X-ray computed tomography (CT) of postmortem human brain tissue provides a blueprint for studying the cytoarchitecture of the human brain and its alterations associated with #NeurodegenerativeDiseases. In PNAS: http://ow.ly/eui350H5uAm
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Large anhydrite crystals from the Naica Mine reveal flaws in the macroscopic crystal that likely stem from a particle-mediated nucleation pathway. http://ow.ly/y5pF50H5uwz
Frog and toad senescence rates may increase with increased mean annual temperature, suggesting that #ClimateWarming may accelerate amphibian aging and exacerbate global amphibian decline. http://ow.ly/hKSY50H5um9
The authors of the Dynamics of Political Polarization Special Feature seek to deepen our understanding of political polarization and related trends, particularly the interplay among these processes at multiple scales, from the local to the international: http://ow.ly/kGAI50H8rvT
Read highlights from this week’s issue of PNAS: We discuss charting Neotropical forest succession, study ancient diets in the Andes, and examine multilingualism and whole-brain activity. http://ow.ly/S2Cx50H5EKW
An imaging system that combines transparent soils with cutting-edge light sheet #microscopy sheds light on previously unseen root–microbe interaction phenomena and accelerates the understanding of how #rhizospheres are formed. In PNAS: http://ow.ly/Ng3b50H5ucZ
A study of 50,000 individuals in the United States and Sweden found that a polygenic score, previously associated with individuals’ likelihood of attainment in higher education, was associated with self-reported and validated voter turnout. In PNAS: http://ow.ly/l3a750H5t7y
Chickadees and tits likely respond to the lack of oxygen and low temperatures in the Qinghai-Tibet Plateau through unique genetic solutions tied to respiration and metabolism, suggesting that parallel evolution can occur among functional traits. In PNAS: http://ow.ly/mg0m50H5sPr
Pedestrian dynamics at the running of the bulls suggest that the presence of the bulls led to instances of runner speed increasing with runner density, in contrast with most pedestrian systems, in which speed decreases with density. In PNAS: http://ow.ly/E6IP50H4LoQ