Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials

Khalesi, Saman; Sun, Jing; Buys, Nicholas; Jamshidi, Arash; Nikbakht-Nasrabadi, Elham; Khosravi‐Boroujeni, Hossein

doi:10.1007/s00394-014-0720-1

Eur J Nutr

2014

DOI: 10.1007/s00394-014-0720-1

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Green tea catechins and blood pressure: a systematic review and meta-analysis of randomised controlled trials

Saman Khalesi

¹

,

Jing Sun

²

,

Nicholas Buys

³

et al.

Abstract: The present meta-analysis suggests that green tea and its catechins may improve blood pressure, and the effect may be greater in those with systolic blood pressure ≥ 130 mm Hg. The meta-analysis also suggests that green tea catechins may improve total and low-density lipoprotein cholesterol.

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Cited by 147 publications

(89 citation statements)

References 55 publications

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5

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“…Our meta-analysis of SBP and DBP levels showed that supplementation of green tea catechins had no significant antihypertensive effect on overweight and obese people. A meta-analysis [ 21 ] showed that there was no significant change in blood pressure in subjects with BMI >30 kg/m 2 , which was consistent with our study. In animal experiments, GT was able to significantly reduce blood pressure in rats.…”

Section: Discussionsupporting

confidence: 92%

Effects of green tea catechin on the blood pressure and lipids in overweight and obese population-a meta-analysis

Wang

¹

,

Xia

²

,

Yu

³

et al. 2023

Heliyon

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…Our meta-analysis of SBP and DBP levels showed that supplementation of green tea catechins had no significant antihypertensive effect on overweight and obese people. A meta-analysis [ 21 ] showed that there was no significant change in blood pressure in subjects with BMI >30 kg/m 2 , which was consistent with our study. In animal experiments, GT was able to significantly reduce blood pressure in rats.…”

Section: Discussionsupporting

confidence: 92%

Effects of green tea catechin on the blood pressure and lipids in overweight and obese population-a meta-analysis

Wang

¹

,

Xia

²

,

Yu

³

et al. 2023

Heliyon

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“….4 , 5 ), which fall when the treatment was stopped. The effect of catechins-enriched diet is in line with previous studies in which an improvement in blood pressure was observed after administration of antioxidants, both in rats and humans 28 , 35 , 36 , 57 – 60 .…”

Section: Discussionsupporting

confidence: 90%

Effects of a catechins-enriched diet associated with moderate physical exercise in the prevention of hypertension in spontaneously hypertensive rats

Seppia

¹

,

Federighi

²

,

Lapi

³

et al. 2022

Sci Rep

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

“…Daily supplementation of w1315 mg green tea catechins (843 mg EGCG) significantly reduced concentrations of TC, LDL cholesterol, and non-HDL cholesterol over the course of 12 mo. These findings are in agreement with the results of most epidemiologic studies (18)(19)(20)(21) and currently published meta-analyses (9)(10)(11)(12) that indicate that the consumption of green tea significantly lowers serum concentrations of TC and LDL cholesterol.…”

Section: Discussionsupporting

confidence: 82%

“…We observed no change in the concentrations of HDL cholesterol after 1 y of GTE supplementation, which is consistent with the data from meta-analysis studies (9)(10)(11)(12) and most of the RCTs (22-43) conducted to date. A few intervention studies (44)(45)(46) found increased concentrations of HDL cholesterol after the ingestion of a green tea beverage or extract.…”

Section: Discussionsupporting

confidence: 79%

Effects of green tea catechin extract on serum lipids in postmenopausal women: a randomized, placebo-controlled clinical trial

Samavat

¹

,

Newman

²

,

Wang

³

et al. 2016

The American Journal of Clinical Nutrition

Get access via publisher Add to collection Cite

Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.

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