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. 2016 Nov 29;7(48):80077-80082.
doi: 10.18632/oncotarget.11374.

Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results

Francesca De Felice  1 , Daniela Musio  1 , Giovanni Luca Gravina  2 , Francesco Marampon  2 , Vincenzo Tombolini  1   3
Affiliations

Adjuvant radiation therapy in stage I seminoma: 20 years of oncologic results

Francesca De Felice et al. Oncotarget. .

Abstract

Aim: To report long term oncologic outcomes after adjuvant radiotherapy (RT) for stage I seminoma.

Method: We reviewed the complete data set for all patients treated at our institute between 1988 and 2005 for stage I seminoma with adjuvant RT after radical orchiectomy .

Results: A total of 85 patients were included. The median follow-up was 15 years. The 20-year overall survival (OS) and relapse free survival (RFS) were 92% and 96.3%, respectively. No severe acute and late complications were recorded. Overall 5.9% of patients had a second unrelated malignancy.

Conclusion: Adjuvant RT is an efficacious and safe treatment in stage I seminoma.

Keywords: chemotherapy; orchiectomy; radiotherapy; stage I seminoma; surveillance.

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Conflict of interest statement

CONFLICTS OF INTERESTS

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1. Kaplan Meier curves of overall survival (OS) and relapse free survival (RFS)
See this image and copyright information in PMC

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